What to look for in a dog toothpaste in 2026
The right dog toothpaste in 2026 has five qualities. First, it is enzymatic, which means it contains the two enzymes (glucose oxidase and lactoperoxidase) that kill the bacteria in the plaque and prevent the plaque from hardening into tartar. Enzymatic toothpaste is the gold standard recommended by the Veterinary Oral Health Council (VOHC) and is the right choice for most dogs. Second, it is safe to swallow, which means it does not contain fluoride (toxic to dogs) or sodium lauryl sulfate (the foaming agent in human toothpaste which dogs cannot spit out).
Third, it is flavored to the dog taste, which means poultry, beef, vanilla mint, or malt. The right way to test the flavor is to put a small amount on your finger and let the dog lick it; if the dog rejects the flavor, switch to a different flavor or a different brand. Fourth, it is approved by the VOHC, which means the toothpaste has been independently tested and shown to reduce plaque and tartar. The right way to verify the approval is to check the VOHC website at vohc.org. Fifth, it is priced within the budget, which means 5 to 20 dollars per tube.
The enzymatic daily brushing picks
For most dogs, the right enzymatic toothpaste for daily brushing is the Petrodex Enzymatic Dog Toothpaste at 6 to 9 dollars per 6.5 oz tube. The toothpaste uses the same dual-enzyme system as the Virbac C.E.T. brand (the most popular enzymatic toothpaste among veterinarians) but at a 30 to 40 percent lower price. The flavor is poultry which most dogs accept. Apply a pea-sized amount to a pet-specific toothbrush (silicone finger brush for small dogs, long-handled brush for medium and large dogs) and brush the outer surfaces of the teeth in small circles for 30 to 60 seconds per side.
The second-best enzymatic toothpaste is the Virbac C.E.T. Enzymatic Toothpaste at 10 to 14 dollars per 2.5 oz tube, the most popular brand among veterinarians, available in 5 flavors. The third-best is the Vet Best Enzymatic Dog Toothpaste at 8 to 11 dollars per 3.5 oz tube, which uses a natural enzyme blend (aloe, neem oil, baking soda) plus the dual-enzyme system, the right choice for dogs with sensitive teeth.
The natural and sensitive picks
For dogs with sensitive teeth or sensitive stomachs, the right natural toothpaste is the Leba III Pet Dental Spray at 15 to 20 dollars per 1 oz bottle. The product is an enzymatic spray that requires no brushing; spray on the dog teeth and gums once a day. The active ingredients are the same dual-enzyme system plus a mineral blend that strengthens enamel. Lift the dog lip, spray 2 to 3 times on each side, and let the enzymes work. The right choice is Leba III for dogs that absolutely reject the toothbrush.
The second-best natural toothpaste is the TropiClean Fresh Breath Dog Toothpaste at 9 to 12 dollars per 4.5 oz tube, which uses a natural ingredient blend (green tea, baking soda, and the dual-enzyme system) and is free of artificial colors, flavors, and preservatives. The third-best is the Burt Bees for Dogs Toothpaste at 7 to 10 dollars per 5 oz tube, with a honey flavor for dogs that reject savory flavors.
The puppy picks
For puppies aged 8 weeks to 6 months, the right toothpaste is the Arm and Hammer for Pets Puppy Toothpaste at 5 to 8 dollars per 2.5 oz tube. The toothpaste is a mild enzymatic paste with a vanilla mint flavor that puppies accept, and it is free of fluoride and SLS. Apply a pea-sized amount to a silicone finger brush (softer than a regular toothbrush and easier to fit in a small puppy mouth) and brush the outer surfaces for 15 to 30 seconds per side. The right time to start is when the puppy is 8 to 10 weeks old.
The second-best puppy toothpaste is the Nylabone Puppy Toothpaste at 5 to 8 dollars per 2.5 oz tube, a mild enzymatic paste with a poultry flavor. The third-best is the Petrodex Puppy Toothpaste at 6 to 9 dollars per 2.5 oz tube, the puppy version of the Petrodex enzymatic paste with a milder flavor and softer formula.
How to brush your dog teeth the right way
The right way to brush a dog teeth is in five steps. First, choose a quiet time and a comfortable location (the floor, the couch, or a small table). Second, apply a pea-sized amount of toothpaste to the brush and let the dog lick it, which introduces the flavor and builds positive association. Third, lift the dog lip and brush the outer surfaces of the teeth in small circles, focusing on the canine teeth and the back molars where plaque builds up the most. Fourth, brush for 30 to 60 seconds per side, which works out to 2 to 3 minutes total. Fifth, end with a reward (a dental chew, a play session, or a small treat).
The right frequency is once a day for the best results, three times a week for moderate results, and once a week for minimum results. The right way to build the habit is to brush at the same time every day and to use a flavored toothpaste the dog enjoys. The right way to handle a resistant dog is to start with a desensitization program: touch the muzzle with a finger, then touch the gums with a finger, then touch the teeth with a silicone finger brush, then touch the teeth with a toothbrush. The desensitization takes 2 to 4 weeks and the right pace is one step per day.
Total cost in 2026 for a dog toothpaste routine is 5 to 20 dollars for the toothpaste per month, 5 to 15 dollars for the toothbrush (replaced every 6 to 12 months), and 10 to 30 dollars for the dental chews per month. The right way to budget is to assume 25 to 65 dollars per month for the full routine.






